They might be the first to actually wound her on panel, but I can't see them beating BM, it doesn't make sense from a power scaling perspective, let alone a narrative perspective.
This is Luffy's journey to take down the yonkos, he took down half of the shichibukai personally one way or another; and has been saying he will take down BM to multiple people for 100s of chapters, BM isn't going down without at least fighting against Luffy properly.