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Medical ninjas’ healing capabilities are not comparable to Hashirama’s cells. Even Tsunade’s seal, which enabled her to survive a direct stab from a Full Body Susanoo’s sword and enabled her to completely regenerate stabbed part of her body in few seconds, is stated to be not comparable to the...

Kakashi used MS more rarely (until the war arc and even than he had fatigue several times) than Sasuke/Madara did. This probably extended lifetime of his eyes. Think of it like a healthy person smoking two packs of cigar per day vs a person with asthma smoking two pack of cigars per month. The...

I agree except for bleeding part. Obito was able to spam his eyes since he had Hashirama’s cells implanted into his body. His body’s regeneration rate far outclassed the damage Mangekyo has done to his body/eyes.