I'm a firm believer that the Nerona family is a race of vampires and their lore will be inspired by Castlevania/Hellsing/Vampire Hunter D series since Mihawk and Imu give off strong vibes from it and One Piece has been getting more demonic with each chapter. Both are also implied to be at the very top of the verse yet they remain complete enigmas which highlights their significance. In Vampire D lore, they're the noble rulers of the world. I know Mihawk - Imu connection has been discussed to death but I just want to point out that he might be inspired by that story.
Alucard is a blond bishounen and characters that looks like that are often depicted as some of the most sadistic villains in seinen anime so I believe a bishounen and blonde Cavendish is foreshadowing that Imu will look like him because Hakuba talks like him and Cavendish is obsessed with Luffy much like Imu who was obsessed with Joyboy.
We know that everything shown about Imu has been feminine like and he's obsessed with flowers. Lili and the lily flowers could be inspired by the vampire queen Lilith and the vampire Lily flower.
Meanwhile, Mihawk resembles a Dracula as his name implies and is implied to be brutal much like Imu.
Vampires are also known for their long lifespans, can shapeshift and appear younger.
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