He might interact with him again, then it’s just the question of who finishes him off- Zoro or Hiyori.
It won’t be a fight though. Look at what the Scabbards did, they basically just walked up and slaughtered Orochi. The guy is fodder. Orochi’s final defeat will be a bit more dramatic, but if it is Zoro and not Hiyori that does it then we’re talking about a one-shot.
It’s also not going to be, if it happens, the end of Zoro’s part in the raid.