On page 5 of chapter 1185, Brook mentions that Candelle was bedridden for several months due to stress after meeting an authority figure who had never appeared in Esperia before. I think this likely implies, as subtext, that she was sexually assaulted. Oda has been engaging quite a bit with the grimmer aspects of human trafficking's purposes, it would be great if he were a good writer, but that isn't the case :/