DR Doffy was a lamb to DR Luffy using G4.
Cracker had G4 Luffy on the run for 11 plus hours, while Nami was there to turn his DF into fuel for Luffy.
The entire point of Cracker being the first major Emperor commander was to represent the MASSIVE step-up in competition.
Doflamingo will return to the story with a stimulus of his own, but implying DR Doffy could get past Queen's hide, or even last more than a few minutes at most.