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Kisame has everything in his arsenal to beat Itachi in the best circumstances for him.

I'm not saying it's likely. I think Itachi wins 6.5/10 times.

But Kisame has a good chance.
Lol but Itachi can use genjutsu to instantly catch Kisame off guard. It took him panels to find out Kurenai had ensnared him, against Genjutsu no Itachi he's getting negged by 3 tomoe.
 

TheAncientCenturion

I will never forgive Oda
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Lol but Itachi can use genjutsu to instantly catch Kisame off guard. It took him panels to find out Kurenai had ensnared him, against Genjutsu no Itachi he's getting negged by 3 tomoe.
Good think you only need a constant break in chakra to free oneself of genjutsu. Kisame, with prior knowledge, orders Samehada to rob chakra from him in small increments to make himself immune to genjutsu.
 
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