Not happening, sorry mate
Luffy is the literal God of the Sun, Joyboy, Chosen Savior of the World
man has God Devil Fruit Awakened, has Future Sight, has Conqueror's, has Advanced Conqueror's, has Advanced Armament, has infinite stamina and endurance with Gear 5th heart beating
this dude can keep fighting like a mad man, breaking all the rules, full on plot armor, until he wins
and crazy Oda can even give him a new power up in the middle of this fight too, just for the hell of it