Well we can't predict Oda's Scenarios, because the possibilities are endless,
But He can't modify the themes & structure of the Story He is trying to tell,
Also this isn't new imo, One Piece have always been about Science vs Dreams,
Everything in One Piece is Scientific, even Sea Kings They were simply Void Century's Villain version of Smile Army,
And that Ancient Mermaid was just their O-Tama who stole control of them from him, which made her known as Poseidon,
Same for DFs, and Races, and how the entire World is Shaped,
Only ones who aren't Scientific are SHs,
Sanji's Love, Usopp predicting Future, Nami predicting Weather, Jinbe talking to Whale Sharks ... etc
They are freaks of nature,
It's a story about how a bunch of dreamers gonna change a World that is so Scientifically manipulated to the point you won't know what was true & what was just lies when Story ends,