No, this is a terrible comparison. The start of Naruto and Sasuke's connection is they went to school together, grew up alongside eachother. Naruto has memories of seeing a young Sasuke by the lake, and has always been interested in him, with the opposite also being true, Sasuke is just more subtle about it. Blackbeard and Luffy have nothing like this connection. Not only do both of them lack an education(okay don't take that serious), Blackbeard is years and years older, closer to Luffy's dad and or father figure Shanks.
As characters, they are completely different in the way they're written. While Sasuke is written to be traumatized and fucked up by his childhood, that causes the characters to ultimately forgive him, Teach is explicitly the opposite. Teach had horrible things happen to him, and his family was genocided. He has no real chip on his shoulder about this. When we see him in the story, he is arguing for optimism, and criticizing pessimists and realists. While some fans want Teach to be vengeful or resentful, we know for a *fact* this isn't a case. Teach offered Ace a position on his ship, and even told Luffy that if he wanted to save Ace, he should try to do so. Of course, it isn't lost on Teach who Ace and Luffy are related too, but he doesn't ultimately care. He was willing to use them to gain a better position for himself, and when they aren't useful in this way, he holds no grudge. If you want a character who is an avenger and is probably just based on Sasuke, you do have Law, who's arc was centered on wanting revenge on Doffy,before it became about him being like, anti government? I don't really think the similarities would extent beyond Dressrosa, but maybe,
Also, I am not entirely convinced that Teach and Luffy have ancestors who were rivals Asura/Indra style yet. I don't think we have a confirmation that Davy Jones is an entirely new person, and not Soyboy's real name. Though, either way, the ultimate destined conflict in OP would be the D's and the CD's, not a generational conflict between the D's, necessarily.