For me powerscaling doesn't need to be considered, it would literally be impossible to draw any kind of 1 vs 1 choreography between Loki and non-Luffy SH. DR makes the victim like 3 times bigger so even base Loki would be like 200 meters tall (I don't even dare to imagine his hybrid and full beast form)
And this is not unimportant, Oda designed Loki being so big while having his role in the arc in mind, which is why he either fighting Goofy alongside the SHs assisting or Imu (who can likely take a much more monstruous form)