Yeah no
The Dragonslayer is able to negate regeneration via injuring the soul, which Alu can't resist so his Regeneration is getting nulled here.
He has around 3 - 8.5 millions souls residing in his body iirc. Unless dragon slayer can negate and kill 1000s of souls at a single time, he's gonna be in for a long day.
Only version of Alucard I see Guts winning against is Post - level 0 where he's expelled all his souls and it's just him on his own. (Level 0 army would overwhelm Guts. Let's just say he arrives after all the souls got burned by hellfire or something). Even then, he's still a very capable fighter who possesses superhuman stats.
High/ Extreme diff either way for this verion only. I'm not to sure on the maths behind both fighter's stats but that should be fair.
Any other version of Alucard will probably stomp