Not only outstat Hades from Saint Seiya, Hades from Kid Icarus, he also has ways to eradicate him, despite being immortal to some degree:
Atomic Destruction/Sub Atomic Destruction: That is basically a basic ability SS characters have, while it would be enough to overcome the regeneration of Hades (Kid Icarus), which shown regeneration is far below that level.
Soul destruction: For the case that Hades (Kid Icarus) will just fight then as soul or astral being, or when he somehow still find a way to regenerate on such a level (Which lacks of feats or statements)
I wonder if Hades (Kid Icarus) is even in a way immortal that he transcend life and death, or Hades (Saint Seiya) could just
kill him. Let us also not forget that he is in a superior Hierarchy to his subordinate, the God of Death Thanatos who could do
this and
this.
There is also something else that is dangerous on Hades. His sword:
Or what stops Hades (Saint Seiya) from painting Hades (Kid Icarus)
There is so much more....