Y'know, I'm not really sure about this. At first I thought "Yonko wreck, Warlords don't" but now I don't think it would be that simple.
Blackbeard only acts if it helps him. He won't provoke Marines without good cause. One day he will aim to destroy the Celestial Dragons, but not until it suits him.
Shanks has shown he'll meet up with the Gorosei, who have ordered genocide. I think face to face, if he saw something like Charloss shooting Hachi the blood would boil and he'd step in, but it's hard to say.
BM and Kaido are just as cruel as a CD. Wouldn't give a fuck about hurting them, but only if they did something to annoy them specifically.
For the Warlords.
Law has obviously shown he wouldn't step in. Jinbei's too aware of what it would cause. Kuma's playing a very long game and would endure it. A series of comedic misunderstandings would lead to Buggy destroying a CD by accident while trying to run away from them.
I genuinely think Hancock, Doflamingo, Moria and Crocodile are all arrogant enough that they'd attack a CD regardless of the circumstances. Crocodile in Marineford tried to attack Whitebeard in the middle of all his allies. And attacked Akainu. He's not really scared of anyone. Doflamingo considers himself a CD anyway, and attacked a Fujitora when he lost his temper. Hancock just absolutely does not give a fuck, plus she absolutely despises them. Only any residual trauma would stop her. And Moria charged into Blackbeard's main island solo ready for a fight over Absalom.
Weevil does what Bakkin tells him to do, and is, well, thick. He'd kill a CD and not even realise it was a big deal.
And i imagine Mihawk would react in pretty much the exact same way as Zoro. Which is extreme violence.