I just hope that this is not another trans-character and you can gladly call me whatever you want for that statement. I stand by it.
Bon Clay being an Okama - cool!
Ivankov and an entire level on Impel Down being Okamas - interesting idea!
Izu being a crossdresser - fine!
Sanji landing on an island full of Okama - ok.
Kiku being a transsexual - ok, but isn't it getting a bit too much now?
Yamato introduced as "son" and now probably being a transsexual, too - just doesn't seem realistic anymore, especially in a pirate world like OP.
At one point the Okama/transsexual theme just isn't new or exciting anymore. It's repetitive.