There is increasingly less evidence this will be a straightforward fight of crew vs crew.
Strawhats will need and have allies in two instances I believe they will clash.
I believe they will fight alongside the Red Hair Pirates the first time and lose. Shanks will die ensuring Luffy’s escape.
The second time I believe they will be fighting alongside revolutions and SWORD Marines.
I’m less confident on the matchups the first time they fight. I also believe Blackbeard has 1 to 3 new subordinates left to collect: Doflamingo, Urouge and Shamrock, depending on when BB usurps Imu.