Nah. One Piece was never a story of a 'misfit turning into someone important' like Naruto. The inherited Will and fate have been emphasized since the beginning of the series. And bloodline doesn't matter in one piece as much as it matters in Naruto. DF system is broken but Oda never went to the level of 'planetary' and no matter how broken DF is, it is useless in seawater.
This chosen stuff never came up pre-time skip. except in marineford and bits of archipelago arc
I started to watch the series for zoro and luffy , random nobodies aiming for the top. with ussop/sanji/nami another random nobodies.
Blood line doesn't matter , Luffy bloodline , Zoro bloodline (I hate to say this as a zoro fan , even if doesn't borrow anything from his lineage , it ruined his character for me) , sanji bloodline , won't be suprised if nami has some too at this point.
Haki and chakra is almost similar , Chakra wasn't planetary level either until 4th great ninja war , watch final one piece get planetary as well. I might not even read it. chakra doesn't recover itself as quickless as haki , it takes days for them to recover could be lite version alternative to Seawater for DF.
DF are broken and so is Kekkai genkai. down side of kekkei genkai being too much chakra consumption , sasuke explained using susanno with the pain in every cell of his body.
But no matter how hard you try to disagree , shounen somehow turns into this kind of mess.