So far, Kizaru has shown 0 things that can get through Kaido's durability, the same goes for his former colleague Aokiji. The noose is tightening around the necks of the Admirals.
The lasers are being absorbed by Chad Yonkou Luffy, avoided by Sentomaru and his regular legs, not even incapacitating him permanently. Franky needed to target Sasaki's weakest point on his body with the same lasers as Kizaru to finally defeat him (a part of his chest), and Sasaki's durability is like 1000x lower than Kaido's scales.
At most, what Kizaru can cause to Kaido is superficial damage if he has Haki Adcoa, but honestly, even if a physical monster like Luffy in G4, after pummeling Kaido for minutes, concluded that his attacks were causing superficial damage, someone physically weaker like Kizaru would cause even shallower damage. Not to mention that superficial damage on Kaido is instantly healed by his insane recovery.