No, not at large.
Tbh I don't see any of them losing against BM or BB just out of the TS, but it would be a close call with all the others depending on the matchup and still with some I don't see them winning. Aokiji might be different since he was so close to Akainu, so I think Aokiji can have a shot with anyone, winning or losing even against the strongest extreme diff.
Talking seriously, Admirals and Yonkou are in the same tier; always said. I fought against that shit of "admiral tier" and "yonkou tier" and it's true now just the same: the tier is one.