One Piece kinda reminds me of James Cameron’s Avatar.
Avatar is the most viewed movie triology, but has had basically no influence on the culture (can’t even think of a single meme from it, and most people can’t even remember the names of any characters besides Jake Sully and Neytiri). Meanwhile, there’s like a million popular memes from Endgame alone.
One Piece may be the most watched anime, but it has had a relatively low influence on the culture when compared to shows like JJK. Hell, even Invincible is used more often in anime memes, and it’s not even an anime