Don't believe Luffy will take on Teach alone , so i bet on Luffy taking on Akainu
Besides Sabo just ate Mera2 in Dressrosa ( 3 arcs ago ) , makes no sense if he gets Awakening ( required to defeat Akainu ) in EOS which is 3 arcs away
( Elbaf , Raftel , vs WG arc ) when Luffy Ace and Teach themselves have no Awakenings after years with their DFs
As for Teach , i believe Luffy + Fujitora will defeat him , but Weevil has to play a role too and i don't see what role he can play in Wano rn , so Weevil might be thrown in there too against Teach
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Idk when will Akainu get defeated though , maybe next arc ? since Oda implied Vivi Sabo Hancock will be in bad situations
But it'll be better if Akainu gets defeated with WG ( after Teach's defeat ) , WG's war will be better if they go down with their strongest force ( Marines , especially now they will get SSG Weapon )
I don't believe Blackbeard Pirates will be that relevant , otherwise Oda wouldn't have given an underwhelming DF to their 2nd strongest ( Shiryu )
There's a very good theory that painted war with WG will be the greatest war in One Piece history , made by Admiral Ryokugyu posted by
@playa4321