The reason why I've got no complaints about people with genuine reasons is that society isn't yet ready to accept people for what they are, which is why people are generally forced to choose a gender that does not align with their biological sex. I am not gonna speak for everyone, but from what I've seen, if you're a male and act like a woman around men, they consider you wired and talk shit about you behind your back—Some people even attack you directly.
This behavior somehow drastically drops, if the same person were to change his gender and becomes a transwoman. The insults don't magically disappear all of a sudden but they'll decrease significantly and some people will even start sympathizing with you. A person who's used to getting trashed for being what he is would obviously enjoy this change.
I don't think it's the right solution for the issue in the grand scheme of things. But if transitioning is gonna make life less miserable for the person suffering, then I don't see why I should complain.