Is this Itachi before his death or the Edo Tensei version?
The Edo Tensei version should theoretically be stronger, since the Itachi who fought Sasuke in Shippuden was already on the verge of death from illness.
???
Based on what is Doflamingo's AP too weak to deal damage to Itachi's Susanoo? Tsunade was breaking Madara's Susanoo with her bare fists and Doflamingo cuts through huge meteors.
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