What about the much deeper grudge between Drake and Queen?
It’s not very important to me. Drake and Queen could have started fighting ages ago if this was the way things were going to go, instead him and Apoo have been going at each other for a very long time now. Drake’s use in Wano just doesn’t suggest that he’s going to be the one to beat one of Kaido’s three top men, he’s been very much just fighting along in the background.
On the other hand, Marco has been a massive deal ever since he showed up on Wano, getting him there was a plot point way back on Zou and he’s a fan favourite. Compare how Marco and Drake have been used since the raid started, ask “which one if these seems more built up to be a main figure in the alliance who defeats a Calamity“ and there’s only one answer- Marco. One of them will have to lose out since Sanji’s getting a Calamity and Jack’s getting dealt with separately, and that someone is always going to be Drake. Drake might be backup, but he’s not the main event.
What about the confrontation between Chopper and Queen spanning multiple acts?
What about the fact that Chopper's eponymous chapter was literally the start of his battle with Queen? The highlight of Chopper's chapter involved him bitchslapping Queen.
Chopper can help out or he can go fight Perospero, but he’s not really relevant to this. He’s only going to be backup in a fight against someone as strong as Queen, not the main figure. Like Killer on the roof.
At any rate, Sanji soloing a fully healthy Queen seems incredibly unlikely to me.
Nobody is soloing a fully healthy Queen cause he’s already been kicked around the place a couple of times by Marco.
The throw away Germa line? It's insignificant in comparison.
No it isn’t. It is an absolutely gigantic Chekhov’s Gun yet to be fired. We already know everything about Queen and Drake’s relationship that we need to know- Drake is a traitor, so Queen wants him dead. That’s the long and short of that plotline. It doesn’t really need to be dwelt on anymore than Drake and Who’s Who need to interact again.
But when a main villain is musing about how he needs to defeat our heroes, looks directly at a picture at one of them and talks about how he knew his father- that is a huge deal. The author’s basically going around those panels with bright red ink saying “FUTURE INTERACTION HERE”.
Especially since this is coming off an arc where Sanji’s relationship with his family, and in particular his fathers- birth and chosen- was so important. Sanji repudiating Judge was one of the biggest factors of WCI. The dramatic conclusion of Sanji and Judge’s relationship was Sanji screaming inJudge’s face to never call him his father again, because the only person who can truly be considered Sanji’s father is Zeff. Sanji’s then went on to be pissed off at any mention of him being a Vinsmoke.
It’s then no coincidence that the very next arc- which unlike WCI is a great big fighting one- one of the strongest villains is doing the thing that really,
really pisses Sanji off- calling Judge his father. And that villain was talking about this in the context of enemies he wants to defeat. Because, in Sanji’s head, saying that Judge is Sanji’s father is insulting not to Sanji, but to
Zeff. And Zeff is the person Sanji loves the most in the world.
Now
that‘s a significant plotline that’s yet to be touched on. We’re talking about something that ties into the very core of one of our main characters. Drake’s nothing compared to that. Sanji’s interaction with King is nothing compared to that- the two had a brief fight ages ago and haven’t cared about each other since. Sanji
needs to beat someone strong, and he
needs to interact with Queen- those two factors are going to intertwine.