We haven’t even seen Queen use hybrid yet, so this is way too premature to say.
I could see Oda having Sandai Kitetsu get broken fighting Kaido and BM, and then Zoro uses “Oden Nittoryu” with Wado and Enma (which Oda introduced a plot point about the two being related for some reason) to imitate Oden and reopen the scar. Zoro gets roughed up the in fight, and Oda uses some chain of events to make it so that Zoro has to fight Queen. Queen also uses Nittoryu, so it would be nerfed Nittoryu Zoro vs Queen, a Nittoryu user. Zoro replaces Sandai Kitetsu with Nidai Kitetsu at the end of the arc