--Doffy a YC3 casually negged oars jr who negged giants and they are VAs IIRC so they are above average gianst also. Simply by this you can see the big difference even in between commander level characters and strong giants.
--Well it is true there can be much stronger giants we have yet to be seen. But unless they are inbetweeners , they won't really be an issue for most top tiers. Someone like Kuzan can freeze bunch of them. Kaido can drop an island. Fuji can continuously bombard them with meteors etc.
--If we see more powerful giants with adv haki and powerful DFs then things will change. That I agree. But for now most giants we have seen are mid.
--I don't think there is that much difference between current Kaido and Kaido at age 40. He should be near prime that time.
For now loki aside , no giant has shown the ability to take this --