If my theory of Luffy, Zoro and Nami vs Lucci, Kaku, Stussy doesn't happens then I could see Lucci, Kaku, Stussy and Sera Kuma vs Zoro and Brook.
How would it go though? I can see it like this, Zoro taking a nap in the Sunny then Kaku appears (basically a recall of Water Seven) then Zoro makes a joke about Kaku being Usopp because of their noses then Zoro snapped to reality and say, "Who the fuck are you?" if Zoro still remembers him that is. Then Zoro and Kaku have a skirmish outside of the Sunny while Lucci Gang are waiting. Brook then ask for Stussy's panties which got rejected and Brook might fight her. Now I would say that even if Zoro is a low top tier, he can't possibly take on Lucci, Kaku, and Sera Kuma at the same time. So most likely that some other Vegapunks might intervened and turn on the switch for Sera Kuma somehow and Kuma turns against CP0 so we have Kuma vs Lucci, Zoro vs Kaku and Brook vs Stussy. Brook should be able to beat Stussy, Zoro should do the same against Kaku. Then Kuma vs Lucci might go either way so Zoro can beat whoever's left standing.
Or you know, classic Oda with the off-screen no mi just for Zoro and Brook to get kidnapped for Vegapunk's lab.:jackaugh: