Normal Uvo would already be ridiculously troublesome for Hisoka. With the same speed, I honestly don't think that Hisoka stands a chance (but it depends on the scenario actually, if he can somehow ambush Uvo, he might have a chance).
People sleep on Uvo's attack power and durability due to the Kurapika's fight, but ET Kurapika is extremely overpowered, especially against the Phantom Troupe (his nen gets boosted by his emotions). Even with 100% enhancement nen, Kurapika still had his arm shattered by BBI... Hisoka's transmuter defenses won't be enough to do the same IMO. FYI, he was seriously injured by a weaker enhancer (Kastro; not sure how much weaker, but apparently he couldn't hold a candle to Uvo).