If Luffy develops a deadly disease than Chopper will save him and that's a different story, but having a magic cure for every side effect from his df aint it, especially if he possibly dies EoS, he wont be dying to the incurable disease like Roger but perhaps from pushing himself too far vs Blackbeard or whoever.
He will probably be very ill at some point after Wano that will nerf him till Chopper finds the cure, and becomes more absent that way