Depends on limits of King Of Hell.
If Zoro can dish Out Ashura in King of Hell Mode I believe it will kill it.
If Zoro fought Kaido with Base King of Hell only then Kaido would take Oden level damage but in the end would get High Diff W as Zoro will run out of time.
But then again Joy Boy also has a time limit seemingly.
Can Luffy finish fresh Kaido?
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All that for two drops of blood
This is a lot more blood.