With Zoro is just too hard to not picture him fighting Shiryu, makes too much sense.
I'm sure Oda will play around with it though. Make Zoro clash with another BB pirate just to find his way to his real matchup which is Shiryu
Imo with their abilities all BBP will jump on the straw hats like how they are doing to the heart pirates, before the straw hats figure a way to counter them and take them on in 1v1, at leaat some of them, hard to see Usopp, Nami, Chopper taking them on in a 1v1, unless someone like Chopper carries medicines and shit for himself not much he can do to counter Doc Q hax.
Or that serves as a first clsdh and they get outright beaten when BBP jump on them.