There is a high likelihood that Smoker and Kuzan will engage in combat due to their opposing positions.
Smoker's sense of pride as a marine and his unwavering hatred for traitors, as evidenced by his confrontation with Vergo, may influence his actions. However, Kuzan presents a unique situation that could potentially challenge Smoker's perspective. Kuzan's actions may demonstrate that sometimes unconventional or questionable methods are necessary to achieve desired outcomes.
As for Tashigi doing something remarkable against them is very low. She may be able to disarm Kuzan if he tries to stab Smoker and that pretty much it because if the fight ever happens. I don't see Kuzan really trying, he has no heart in the battle and is using it to cover up his hidden agenda. Kuzan is using the blackbeard pirates period.