Oi oi oi, I just realised Tobirama is a bit like Hitler, should we really go down that road with such a logic
But... Essentially, yes, every Uchiha turned out batshit crazy. Can't really name a single normal one. Maybe Shisui comes closest, but not even. If you think about it, the craziness started out with Itachi. BUT he didn't even plan for Itachi to be "good", originally he wrote him to be evil, so that was the essential thread which started the Uchiha silliness. Then continued by Sasuke, Obito, Madara.
To be honest, Kishimoto just got eaten by his own plot. And his characters. I will forever love Naruto despite all of it though, says a lot.