No, Sanji cannot hurt Kaido. Kaido is one of the strongest characters in the One Piece universe and is considered to be one of the Yonko, or four strongest pirates in the world. He has immense physical strength and durability, as well as powerful Devil Fruit abilities. Sanji, on the other hand, is a skilled martial artist but does not possess any superhuman powers or abilities. Therefore, it is highly unlikely that he would be able to hurt Kaido in any meaningful way.