I personally still think that Yamato’s gender is a she. Yamato’s obsession of Oden is on the whole level, especially when she says “Oden is a man, right? So I become a man too.” That means if Oden were a woman she would have been a woman too. Not to mention this:
Pretty much shows that she knows she is Yamato. Oden is just a role she took it literally. And if Yamato is considered a trans-man and as a “he”, then it would be better in Monet’s case, especially the MFMM part. The previous pattern could be MFMM, but it was pre-timeskip. Post timeskip, Oda reversed it to be MMFM. It fits especially if pre-timeskip is pretty much mirroring the post-timeskip. So after Jinbe (M) & Yamato (M) we can have Monet before the final male. And I think it’s a win win situation, especially if MFMM pattern is too predictable. Oda can just simply mirror it, and make Yamato the ambiguous situation.
For Yamato & wolf part, we can consider that Oda may combine both of Japanese & Western culture. Remember Sodom & Gomorrah back then during Enies Lobby? A fan asked in SBS whether they will be killed by World Govt because the real Sodom & Gomorra were destroyed by God in Old Testament, Oda simply answered that One Piece’s story isn’t that deep, but he surely took their name from the bible. So seeing how Yamato’s hybrid form is sort of she-wolf look, Oda may intentionally combine werewolf & Ooguchi no Magami into Yamato. Here’s the interesting thing:
That’s from Strong World movie back then in 2009. Oda pretty much hinted about Kaido & Yamato’s fight. Oda wants to make Kaido & Yamato the complete opposite. I kinda believe that Oda wanted to make a nakama who is based on werewolf without the needs to use full moon to transform, but also can connect to Japanese lore. That’s why Oda took the Ooguchi no Magami fruit to be Yamato’s, and basically minks are beta test for Yamato.