Based on hax i see no one in Naruto beating here someone like Aizen for example. His Hogyoku gives him a unfair regeneration advantage, also most of the abilities are soul-raping. There is no valid reason why his Reijatsu wouldn´t kill many Naruto characters just by Aizen his presence. There are also people like Yamamoto, Ichibe, Yhwach etc. But we don´t need to go that far. Someone like Baraggan already is cancer for the Narutoverse. Based on destruction powers i would give Naruto the advantage, but based on Hax they don´t have a realistic chance.
Destruction rarely plays into this as soon as hax comes around. It is good for scaling, but the use of destruction ends when hax begins.