My guess is that at least Luffy and Zoro will get major powerups, Luffy will probably pull out Gear 5 and Zoro will pull out Asura or some other new form and they'll beat Kaido because of that. It's also possible the other SNs will get new powerups too.
About Big Mom i believe that she will freak out and try to escape wano after she sees Kaido getting beaten and she either will be dealt with in the next arc or by someone else who comes across her while she is trying to make her escape (possibly the new Marine weapons or an Admiral)
About Big Mom i believe that she will freak out and try to escape wano after she sees Kaido getting beaten and she either will be dealt with in the next arc or by someone else who comes across her while she is trying to make her escape (possibly the new Marine weapons or an Admiral)