Sure, but Oda already indirectly stated that Luffy will be the one to defeat Big Mom and it will be after Kaido. So, it's very likely that she will leave Wano and visit Elbaf one last time. That's where she grew up and that's where her story should end.
I think Big mom will revert back to her O-Lin state, will somehow be healed from her illness by Chopper and return back to her family in WCI.