It'll be luffy+zoro+yamato vs kaido.
Yamato needs to build a chemistry with luffy and zoro while fighting kaido, because she is like them, all they can do is fight.
Also yamato needs to serve the role of telling how much of a danger kaido really is, in a similar way to how tribol was hyping up doflamingo and his demonic willpower.
Most people seem to forget about kaido's sheer willpower, he was defeated 7 times, endured a 1000 torture, caught 18 times by marines and enemy ships, sentenced to death 40 times, and he was experimented on... Yet his will never broke.
Most antagonists throughout the series get their wills broken after 1 or 2 defeats, fisher freaking tiger got his will broken in his deathbed and died crying in regret, moria, don chinjao...
Kaido cannot be defeated in a 1v1, and even if he got defeared he needs to be killed, otherwise he will just come back again.