I'm expecting Queen x Sanji to be extreme diff, we need to see Mr. Prince giving his all and he's fighting a YC2 now, luffy had difficulties against a YC3.
Also, as @Light_428 said, i don't think RS is enough to defeat a Calamity. It'll be very disappointing if Oda do this.
As we see with Ulti, the best way to take Ancient Zoans down it's internal damage, so Ryou would be a perfect power-up for Sanji. Unfortunaly, this seems very unlikely now, the only chance would be for Queen to have adv.CoA and Sanji learn during battle (we've already seen him copy skills from opponents like Gepo).
Also, as @Light_428 said, i don't think RS is enough to defeat a Calamity. It'll be very disappointing if Oda do this.
As we see with Ulti, the best way to take Ancient Zoans down it's internal damage, so Ryou would be a perfect power-up for Sanji. Unfortunaly, this seems very unlikely now, the only chance would be for Queen to have adv.CoA and Sanji learn during battle (we've already seen him copy skills from opponents like Gepo).